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Optimized Wavefront versus Topography-guided Customized Ablation for Compound Myopic Astigmatism: A Prospective Randomized Clinical Trial
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| A Tajabad , G Baradaran-Rafii , MM Sadoughi , M Aghazadeh Amiri , A Ashnagar |
| OD Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran |
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Abstract: (1027 Views) |
Purpose: To compare the visual outcome between wavefront-optimized (WFO) and topography-guided customized ablation (T-CAT) for compound myopic astigmatism.
Methods: This double blind, prospective clinical trial study comprised 40 eyes (21 patients) with compound myopic astigmatism. Myopia was considered between 1 to 8 diopters and astigmatism was considered between 1 to 3 diopters. Patients were randomly divided into two groups: 1) the wavefront optimized group and 2) the topography-guided group. All surgeries were done with Allegretto WaveLight® EX500laser eximer. Visual acuity, refractive error, corneal aberrations, ocular high order aberrations and corneal asphericity were measured before and 6 months after surgery. The results were compared between the two groups.
Results: Six months after surgery, the best corrected visual acuity was similar in two groups. Mean spherical equivalent refraction was -4.33 ± 1.7D and -4.13 ± 1.61 D (P=0.528) to -0.06 ± 0.14 D and -0.04 ± 0.09D (P=0.586) in wavefront optimized and topography-guided groups after surgery. Less stromal tissue was ablated in the topography-guided group than in the wavefront optimized group (P = 0.969). There was no significant difference between the 3rd and 4th grade corneal aberrations between the two groups before and after the surgery (P>0.05). Corneal spherical aberration was increased in both groups. This increase was higher in the WFO group (P = 0.798). Higher order aberrations increased from 0.35 ± 0.14 μm and 0.35 ± 0.11 μm (P=0.496) to 0.52 ± 0.15μm and 0.49 ± 0.16 μm (P=0.786) in the WFO and T-CAT groups, respectively. Corneal asphericity increased in group two, which was higher in the WFO group (P=0.679).
Conclusion: The results of topography-guided and wavefront optimized treatments with Allegretto eximer laser were similar in the correction of compound myopic astigmatism, but TCAT induced fewer HOAs. |
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| Keywords: Compound Myopic Astigmatism, Corneal Asphericity, Higher-Order Aberrations, Topography-Guided Customized Ablation, Wavefront Optimized |
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Full-Text [PDF 211 kb]
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Type of Study: Research |
Subject:
Ophthalmology
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