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:: Volume 25, Issue 3 (Spring 2021) ::
3 2021, 25(3): 244-253 Back to browse issues page
Phosphodiesterase Inhibitors and Eye
Abstract:   (3613 Views)
Nowadays, Phosphodiesterase inhibitors (such as Sildenafil, Tadalafil, Vardenafil, and Avanafil) are used to treat erectile dysfunction in men and pulmonary arterial hypertension. There have been numerous reported ocular side effects of these drugs including anterior ischemic neuropathy, central serous chorioretinopathy, retinal hemorrhage, retinal vein occlusion, and retinal artery occlusion. Also, after taking phosphodiesterase inhibitors, various subjective vision complaints, such as Cyanopsia, blurred vision, diplopia, and photopsia are expressed by patients. We extensively searched phosphodiesterase inhibitors ocular side effects in the literature, using PubMed and Medline. In this review article, we classified the ocular side effects of these drugs and the controversies in the reports, the mechanism of action, paraclinical findings, as well as animal studies in this field.
Keywords: Nonarteritic Anterior Ischemic, Phosphodiesterase Inhibitors, Sildenafil, Tadalafil
Full-Text [PDF 385 kb]   (367 Downloads)    
Type of Study: Review | Subject: Ophthalmology
ePublished: 2021/05/31
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Phosphodiesterase Inhibitors and Eye. 3 2021; 25 (3) :244-253
URL: http://binajournal.org/article-1-1092-en.html

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Volume 25, Issue 3 (Spring 2021) Back to browse issues page
مجله چشم‌پزشکی بینا Bina Journal of Ophthalmology
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